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 Publications are separated in two sections:

> Publications in scientific journals, Presentations & Posters at scientific meetings
> White Papers, Brochures & Meeting Impressions

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Publications, Presentations & Posters

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Download the complete publication

Characterization and evaluation of an integrated quality monitoring system for online quality assurance of external beam radiation therapy

Download the complete JACMP publication about the comprehensive evaluation of the new large field ion chamber transmission detector, Integral Quality Monitor (IQM), for online external photon beam verification and quality assurance.
Download the full presentation

Delivery errors detectability with IQM

Livia Marrazzo and her colleagues at the AOU Careggi in Florence evaluated the the correla9on between the changes in the detector output signal induced by small delivery errors with other metrics, such as the γ passing rate and the DVH variations
They concluded that IQM is capable of detecting small delivery errors and that it exhibits a good correlation with other metrics currently used to determine the quality of a treatment plan.
Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.
Download the full presentation

Verifying Total Body Irradiation using the IQM System

Gabriele Guidi and his colleagues from Az. Ospedaliero Universitaria di Modena evaluated the use of IQM for the verification of TBI treatments.
They investigated the influence of the IQM Detector on depth dose curves and beam profiles for an extended SSD of 170cm. The presentation outlines the considerations that should be applied when utilizing IQM for TBI verification. They concluded that IQM can be used for TBI verifcation
Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.
Download the full presentation

Integrating the IQM into a commercial planning system

Bruce Perrin and his colleagues at the Christie Hospital investigated potential challenges when integrating IQM into a commerical planning system.
They compared data measured in a waterphantom with and without the IQM detector for varioius energies (6,10 & 6FFF). They evaluated the IQM data against clinical models in Pinnacle 9.8 and analyzed the magnitude of adjustments assessed. They finally verified their results by delivering various treatment plans to the Delta 4 through IQM.
Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.
Download the full presentation

Pre-clinical tests of the IQM System

Marlies Pasler and her colleagues at the Lake Constance Radiation Oncology Center in Friedrichshafen, Germany investigated the potential of the IQM System to catch errors before they become clinically relevant. They also checked if IQM would help them to improve the efficiency of their processes and finally they checked if IQM would replace their current pre-treatment QA.
They concluded that IQM could improve the efficiency of their workflow and that the error detection capabilities are sufficient for clinical practice.
Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.
Download the full poster

Beam Delivery Check and In-Vivo Dosimetry during Breast Radiotherapy Treatment

Cinzia Talamonti and her colleagues from the University of Florence, Italy verified the delivery of the prescribed dose during radiotherapy treatment using the IQM in combination with portal imaging together with the software SoftDiso (Best Medical Italy Srl) for in-vivo measurements. They evaluated the ability of detecting positional and delivery errors intentionally introduced during breast treatments.
Download the full poster that was shown during the AIFM Conference in Perugia, Italy in February 2016.
Download the full poster

Evaluation of an Integral Quality Monitor device for monitoring real-time delivery

Gloria Miori1, Andrea Martignano and their colleagues from Azienda Provinciale per i Servizi Sanitari in Trento, Italy analyzed the use of the IQM System for real-time beam delivery control. They evaluated the IQM beam attenuation and IQM's ability to detect VMAT delivery errors. They concluded that the IQM beam attenuation can be considered to be homogenous in both X and Y directions and the machine-specific beam attenuation percentage could be used to rescale treatment plan dose for clinically IQM use. IQM shows appreciable features in detecting real-time errors and for time-saving QAs.
Download the full poster that was shown during the AIFM Conference in Perugia, Italy in February 2016.
Download the full poster

Reproducibility and sensitivity of IQM: A real-time monitoring device for complex radiotherapy treatments

Chiara Arilli, Cinzia Talamonti, Livia Marrazzo and their colleagues from the AOU Careggi, Florence, Italy evaluated the output signal reproducibility and sensitivity in detecting small errors in delivery parameters of IMRT step and shoot treatments using the IQM System as well as the correlation between IQM signal variations and 3Dγ, 2Dγ and DVH parameters.
Download the full poster that was shown during the AIFM Conference in Perugia, Italy in February 2016.
Download the full poster

In-Vivo Dosimetry of Stereotactic Radiation Therapy using the IQM System

Jianguo Qian from the Johns Hopkins University, Baltimore draws the preliminary conclusion that IQM is a stable dosimetric system and can detect dosimetric deviations caused by small leaf errors in stereotactic radiation therapy. The sensitivity to leaf errors is more pronounced for relatively small fields (i.e., small targets) in SBRT. IQM appears to be more sensitive than Mapcheck2 to small leaf errors in SBRT of small targets while showing similar sensitivity in SBRT of relatively large targets.
Download the complete poster that was shown at the ASTRO 57 meeting in San Antonio, Texas
Downlaod the complete presentation

Performance Study of an automated real-time monitoring system for SBRT treatments

Makan Farrokhkish from the Princess Margaret Cancer Centre, Toronto states that IQM is well suitable to verify state-of-the-art SBRT treatments utilizing FFF Rapid Arc treatments on a Varian TrueBeam linear accelerator
Download the full presentation that was held at the iRT booth during the ASTRO 57 meeting in San Antonio, Texas
Download the complete presentation

Real-time detection of deviations in radiotherapy beam delivery using a head-mounted detector

Martijn Kusters from Radboud UMC, Nijmegen, The Netherlands states that IQM enables a clinic to do real-time, intra-fraction monitoring of beam delivery. The error sensitivity and specificity can be expected to be sufficient for clinical practice, and performs at least as well as their current equipment (Scandidos Delta 4)
Download the full presentation that was held at the iRT booth during the ASTRO 57 meeting in San Antonio, Texas
Click to load the full article

Medical Physics Web: IQM offers intra-fraction beam monitoring

Read the article in Medical Physics Web about IQM as a completely new approach to radiotherapy QA as a real-time beam verification system that monitors the accuracy of radiation delivery throughout each patient treatment without any user interaction.
Download the full poster

Monte Carlo Study of an Integral Quality Monitoring (IQM) System

Oluwaseyi Oderinde from the University of the Free State, South Africa developed modelled the IQM using the BEAMnrc component module. this model stands as a basis for Monte Carlo study of the IQM system.
Download the complete poster that was shown at the SAAPMB conference in Bloemfontein, South Africa.
Download the full poster

Testing IQM: A system for real-time monitoring of complex radiotherapy treatments

Stefania Pallotta from University of Florence, Italy evaluated the IQM during the pre-clinical testing. She concludes that IQM provides optimal performance for signal reproducibility of complex IMRT plans. IQM is capable of detecting small errors in MU and leaf positions sufficient for clinical practice
Download the complete poster that was shown at the IEEE conference in Milano, Italy
Download the complete presentation

Efficient and Enhanced QA Testing of Linear Accelerators using a Real-time Beam Monitor

Mr. Andrew Jung. (Member of the IQM development team at the Princess Margaret Cancer Centre in Toronto) evaluated the possibility to utilize the IQM system for a variety of Linac QA purposes. Download the full presentation that was held at the iRT booth during the AAPM 2015 meeting in Anaheim, CA
Download the full poster

In Vivo Dosimetry of Conventional and Rotational Intensity Modulated Radiotherapy Using Integral Quality Monitor (IQM)

Mrs. Lan Lin, Medical Physicist at Johns Hopkins University evaluated the accuracy,sensitivity and constancy of the IQM for conventional intensity modulated radiationtherapy (IMRT) and rotational volumetric modulated arc therapy (VMAT).
Download the complete poster that was shown.at the AAPM 2015 Meeting in Anaheim, CA.
Download the complete presentation

Online quality assurance of external beam radiation therapy with an integrated quality monitoring system

Dr. David Hoffman (Resident Physicist) at UC Davis evaluated the stability and accuracy of each feature of the IQM.
Download the full presentation that was given.at the AAPM 2015 Meeting in Anaheim, CA.
Download the complete presentation

Initial Evaluation of the Integral Quality Monitor (IQM)

Mr. Bruce Perrin, Medical Physicist from The Christie Hospital in Manchester validated the effectiveness and reliability of the IQM to monitor the correct delivery of daily fractions.
The presentation was given at the UKRO (United Kingdom Radiation Oncology) Conference in Birmingham, UK
Download the complete presentation

Response Characteristics of a Large-Area Ion Chamber with Various Radiotherapy Beams

Download the full presentation about the response characteristics of the IQM system with different beams. This presentation was held by Mr. Makan Farrokhkish, B.Sc. (Member of the IQM development team) at the World Congress on Medical Physics & Biomedical Engineering 2015 in Toronto
Download the complete presentation

Quality Assurance with the IQM system - the Radboud UMC experience

Richard Canters from Radboud UMC, Nijmegen, The Netherlands participated in the pre-clinical evaluation of the IQM system.
He found out that IQM detects small errors in beam delivery with respect to precalculated beams, it detects small errors during a treatment course with respect to reference beams, IQM operates with almost no user interaction necessary and that it closes the TPS – R&V – Linac circle.
Download the full presentation that was held at the iRT booth during the3rd ESTRO Forum in Barcelona, Spain.
Download the complete presentation

Preliminary tests with the IQM system - the University of Florence experience

Dr. Stefania Pallotta states that IQM provides an optimal performance for IMRT QA.
Intra-fractional %STD of 0.04% and inter-fractional %STD of up to 0.36% for complex IMRT cases over a period of multiple weeks are the results of this study.
Download the full presentation that was held at the iRT booth during the 3rd ESTRO Forum in Barcelona, Spain
Download the complete publication

An integral quality monitoring system for real-time verification of intensity modulated radiation therapy

Download the full publication by the IQM project team at the Princess Margaret Hospital, Toronto. This article was published in 2009 as a proof of concept for the IQM system.

Flyers, Brochures & Meeting Impressions

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Download the White Paper

IQM White Paper: Signal Reproducibility

The first IQM White Paper outlines the signal reproducibility tests performed during the IQM installations at our research partner sites, as well as additional tests carried out during the pre-clinical evaluation of the IQM System. Download the IQM White paper to learn about the exceptional signal reproducibility of the IQM system.
Download the White Paper

IQM White Paper: Signal Linearity and Dose Rate (In-) Dependence

The second IQM White Paper outlines the results performed during IQM acceptance testing at our research partner sites. During every IQM installation the signal linearity and dose rate dependence is tested. Download the IQM White paper to learn about the exceptional signal linearity and dose rate independence of the IQM system.
Download the IQM Technology Brochure

IQM Technology

A true innovation combining advanced technical functionality with a beautiful design and ultimate quality
Download the IQM Applications Brochure

IQM Applications

Fully automated background monitoring - no additional workload
Download the IQM Reference Brochure

IQM References

IQM has been thoroughly tested by some of the world's leading Radiation Therapy Centers
A few impressions...

AAPM 57 Anaheim

iRT showcased the current research status of the IQM System at the 57th AAPM Meeting in Anaheim.
Download this PDF for some impressions of the meeting, our in-booth talks and the IQM related posters.
A few impressions...

ASTRO 57 San Antonio

iRT showcased the IQM System for the first time at ASTRO at the 57th ASTRO Meeting in San Antonio.
More than 220 leads in 3 days - download this PDF for some impressions of the meeting...
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